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| Nomenclature |
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Symbol:
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Gpr98tm1Msat
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Name:
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G protein-coupled receptor 98;
targeted mutation 1, Makoto Sato
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MGI ID: |
MGI:3527179 |
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Synonyms: |
Vlgr1- |
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Gene:
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Gpr98
Location:
Chr13:81095068-81633154 bp, - strand
Genetic Position: Chr13,
42.18 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:95518
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Parent Cell Line:
| E14.1 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A neomycin resistance gene replaced exons 2-4. RT-PCR showed that transcripts from mutant animals lacked these exons, and that exon 1 was ligated to exon 5. A stop codon was created by frame shifting in the resulting truncated mRNA transcribed from the direct connection of exon 1 to exon 5, and would result in a 14 amino acid peptide, if any. (J:95518)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Gpr98 Mutation:
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4 strains or lines available |
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| References |
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Original: |
J:95518
Yagi H et al.,
"Vlgr1 knockout mice show audiogenic seizure susceptibility."
J Neurochem 2005 Jan;92(1):191-202
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All: |
3 reference(s)
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Analysis Tools
