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| Nomenclature |
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Symbol:
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Prkcitm1Kido
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Name:
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protein kinase C, iota;
targeted mutation 1, Yoshiaki Kido
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MGI ID: |
MGI:3526850 |
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Synonyms: |
alphaPKClambdafloxed, PRClambdaflox |
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Gene:
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Prkci
Location:
Chr3:30995747-31052741 bp, + strand
Genetic Position: Chr3,
14.65 cM
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Focal segmental glomerulosclerosis in Prkcitm1Kido/Prkcitm1.1Kido Tg(Nphs1-cre)33Mska/0 mice
Show the 2 image(s) involving this allele.
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:95378
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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LoxP sites flanked exon 5 by homologous recombination. (J:95378)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Prkci Mutation:
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56 strains or lines available |
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| References |
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Original: |
J:95378
Hashimoto N et al.,
"PKClambda regulates glucose-induced insulin secretion through modulation of gene expression in pancreatic beta cells."
J Clin Invest 2005 Jan;115(1):138-45
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All: |
6 reference(s)
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Analysis Tools
