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| Nomenclature |
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Symbol:
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Sdhdtm1Jlob
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Name:
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succinate dehydrogenase complex, subunit D, integral membrane protein;
targeted mutation 1, Jose Lopez-Barneo
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MGI ID: |
MGI:3526521 |
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Synonyms: |
SDHD- |
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Gene:
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Sdhd
Location:
Chr9:50596340-50603849 bp, - strand
Genetic Position: Chr9,
27.75 cM, cytoband B
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:95252
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
| |
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Exons 2-4 were replaced with a neomycin resistance gene. (J:95252)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Sdhd Mutation:
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8 strains or lines available |
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| References |
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Original: |
J:95252
Piruat JI et al.,
"The mitochondrial SDHD gene is required for early embryogenesis, and its partial deficiency results in persistent carotid body glomus cell activation with full responsiveness to hypoxia."
Mol Cell Biol 2004 Dec;24(24):10933-40
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All: |
2 reference(s)
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Analysis Tools
