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| Nomenclature |
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Symbol:
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Kat5tm1Jwl
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Name:
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K(lysine) acetyltransferase 5;
targeted mutation 1, John W Lough
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MGI ID: |
MGI:3526095 |
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Synonyms: |
Tip60- |
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Gene:
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Kat5
Location:
Chr19:5603017-5610094 bp, - strand
Genetic Position: Chr19,
4.34 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:125164
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: The targeting vector replaced 2,787 bp, including 193 bp of the promoter and exons 1-9, with the neomycin-resistance cassette in reverse orientation. (J:125164, J:153728)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Kat5 Mutation:
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3 strains or lines available |
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| References |
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Original: |
J:125164
Gorrini C et al.,
"Tip60 is a haplo-insufficient tumour suppressor required for an oncogene-induced DNA damage response."
Nature 2007 Aug 30;448(7157):1063-7
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All: |
2 reference(s)
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Analysis Tools
