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| Nomenclature |
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Symbol:
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Btg2tm1Spo
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Name:
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B cell translocation gene 2, anti-proliferative;
targeted mutation 1, S Paul Oh
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MGI ID: |
MGI:3525505 |
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Synonyms: |
Btg2-, PC3/Tis21- |
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Gene:
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Btg2
Location:
Chr1:134075170-134079120 bp, - strand
Genetic Position: Chr1,
58.1 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:95124
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Parent Cell Line:
| J1 (ES Cell) |
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Strain of Origin:
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129S4/SvJae
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A neomycin resistance gene replaced exon 2, which contains sequence encoding APRO homology boxes A and B. Northern blot demonstrated the lack of transcript in mutant kidney samples. (J:95124)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Btg2 Mutation:
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2 strains or lines available |
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| References |
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Original: |
J:95124
Park S et al.,
"B-cell translocation gene 2 (Btg2) regulates vertebral patterning by modulating bone morphogenetic protein/smad signaling."
Mol Cell Biol 2004 Dec;24(23):10256-62
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All: |
3 reference(s)
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Analysis Tools
