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| Nomenclature |
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Symbol:
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Park7tm1Cai
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Name:
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Parkinson disease (autosomal recessive, early onset) 7;
targeted mutation 1, Hubaibin Cai
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MGI ID: |
MGI:3522482 |
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Gene:
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Park7
Location:
Chr4:150897133-150914437 bp, - strand
Genetic Position: Chr4,
81.52 cM, cytoband E1
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:141628
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129X1/SvJ
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: The first coding exon was replaced with a selection marker flanked with loxp sites. QPCR and Western blot analysis confirmed the absence of gene products. (J:141628)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:141628
Chandran JS et al.,
"Progressive behavioral deficits in DJ-1-deficient mice are associated with normal nigrostriatal function."
Neurobiol Dis 2008 Mar;29(3):505-14
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All: |
1 reference(s)
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Analysis Tools
