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| Nomenclature |
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Symbol:
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Lama2tm1Eeng
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Name:
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laminin, alpha 2;
targeted mutation 1, Eva Engvall
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MGI ID: |
MGI:3522319 |
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Synonyms: |
dyw, Lama2dy-W |
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Gene:
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Lama2
Location:
Chr10:26981288-27616942 bp, - strand
Genetic Position: Chr10,
14.23 cM, cytoband A4-B1
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:49435
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Parent Cell Line:
| CJ7 (ES Cell) |
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Strain of Origin:
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129S1/Sv-Oca2+ Tyr+ Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutation: | |
Insertion |
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Mutation details: Insertion of a lacZ and neomycin resistance cassette 23 bp downstream of the ATG start site disrupts gene transcription. (J:48073, J:49435)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:49435
Kuang W et al.,
"Merosin-deficient congenital muscular dystrophy. Partial genetic correction in two mouse models."
J Clin Invest 1998 Aug 15;102(4):844-52
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All: |
19 reference(s)
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Analysis Tools
