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| Nomenclature |
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Symbol:
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Tg(Gfap-cre)73.12Mvs
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Name:
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transgene insertion 73.12, Michael V Sofroniew
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MGI ID: |
MGI:3522215 |
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Synonyms: |
GFAP-Cre, mGFAP-Cre |
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Transgene:
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Tg(Gfap-cre)73.12Mvs
Location:
unknown
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Transgene origin |
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Strain of Origin:
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(BALB/c x C57BL/6NHsd)F1
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Transgene description |
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Transgene
Type: | |
Transgenic (Cre/Flp) |
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Mutation: | |
Insertion |
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Mutation details: The bacterial Cre recombinase gene was inserted into the first exon of an expression cassette (clone 445) that contains all the introns, promoter regulatory elements, exons, and 2.5 kb of 5' and 2 kb of 3' flanking DNA of the astroglia-specific mouse glial fibrillary acidic protein gene. GFAP is not expressed from the transgene due to deletion of part of exon 1. (J:94543)
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Recombinase activity
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:94543
Garcia AD et al.,
"GFAP-expressing progenitors are the principal source of constitutive neurogenesis in adult mouse forebrain."
Nat Neurosci 2004 Nov;7(11):1233-41
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All: |
13 reference(s)
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