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Notch2tm1Rko
Targeted Allele Detail

Nomenclature
Symbol: Notch2tm1Rko
Name: notch 2; targeted mutation 1, Raphael Kopan
MGI ID: MGI:3522155
Synonyms: N2flox
Gene: Notch2   Location: Chr3:98013538-98150367 bp, + strand    Genetic Position: Chr3, 42.42 cM
Mutation
origin
Germline Transmission: Earliest citation of germline transmission: J:94517
Parent Cell Line: Not Specified (ES Cell)
Strain of Origin: Not Specified
Mutation
description
Allele Type:   Targeted (Floxed/Frt)
Mutation:   Not Specified
    The molecular details of this allele are not published.
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR) Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation: Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Notch2 Mutation: 17 strains or lines available
References
Original: J:94517 Pan Y et al., "gamma-secretase functions through Notch signaling to maintain skin appendages but is not required for their patterning or initial morphogenesis." Dev Cell 2004 Nov;7(5):731-43
All: 10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/08/2013
MGI 5.13
The Jackson Laboratory