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| Nomenclature |
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Symbol:
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Hoxa13tm1Jwi
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Name:
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homeobox A13;
targeted mutation 1, Jeffrey W Innis
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MGI ID: |
MGI:3521726 |
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Synonyms: |
Hoxa13Ala28 |
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Gene:
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Hoxa13
Location:
Chr6:52257694-52260803 bp, - strand
Genetic Position: Chr6,
25.41 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:94412
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Parent Cell Line:
| AB1 (ES Cell) |
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Strain of Origin:
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129S7/SvEvBrd-Hprt+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-in) |
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Mutation: | |
Insertion |
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Mutation details: Homologous recombination was used to insert 10 additional alanine residues into repeat III, bringing the largest polyalanine sequence up to 28 residues. (J:94412)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Hoxa13 Mutation:
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1 strain or line available |
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| References |
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Original: |
J:94412
Innis JW et al.,
"Polyalanine expansion in HOXA13: three new affected families and the molecular consequences in a mouse model."
Hum Mol Genet 2004 Nov 15;13(22):2841-51
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All: |
1 reference(s)
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Analysis Tools
