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| Nomenclature |
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Symbol:
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Tg(Nkx2-5-cre)9Eno
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Name:
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transgene insertion 9, Eric N Olson
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MGI ID: |
MGI:3514028 |
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Synonyms: |
Nk9, Nkx2.5::Cre |
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Transgene:
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Tg(Nkx2-5-cre)9Eno
Location:
unknown
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Transgene origin |
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Strain of Origin:
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Not Specified
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Transgene description |
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Transgene
Type: | |
Transgenic (Cre/Flp) |
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Mutation: | |
Insertion |
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Mutation details: A 2.5 kb fragment containing the mouse Nkx2.5 basal promoter and cardiac enhancer was placed in front of an NLS-cre cassette. Expression of cre is seen in developing heart, pharynx, and some liver cells. Three lines were created and line 9, which had the highest levels of cre recombination in the heart, was selected for use. (J:94514)
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Recombinase activity
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:94514
McFadden DG et al.,
"The Hand1 and Hand2 transcription factors regulate expansion of the embryonic cardiac ventricles in a gene dosage-dependent manner."
Development 2005 Jan;132(1):189-201
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All: |
12 reference(s)
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