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| Nomenclature |
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Symbol:
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Itga7tm1Burk
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Name:
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integrin alpha 7;
targeted mutation 1, Dean J Burkin
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MGI ID: |
MGI:3512077 |
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Synonyms: |
alpha7-, alpha7betagal, alpha7integrinLacZ |
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Gene:
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Itga7
Location:
Chr10:128933813-128958277 bp, + strand
Genetic Position: Chr10,
77.2 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:100236
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exon 1 was replaced with a lacZ/neo cassette to permit expression of the beta-galactosidase reporter gene from the alpha7 integrin promoter. Absence of gene product was confirmed by immunohistochemistry, Western blot analysis, and QRT-PCR. (J:100236)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:100236
Flintoff-Dye NL et al.,
"Role for the alpha7beta1 integrin in vascular development and integrity."
Dev Dyn 2005 Sep;234(1):11-21
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All: |
12 reference(s)
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Analysis Tools
