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| Nomenclature |
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Symbol:
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Ddb2tm1Pra
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Name:
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damage specific DNA binding protein 2;
targeted mutation 1, Pradip Raychaudhuri
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MGI ID: |
MGI:3511965 |
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Synonyms: |
DDB2- |
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Gene:
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Ddb2
Location:
Chr2:91211572-91236982 bp, - strand
Genetic Position: Chr2,
50.56 cM, cytoband E1
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:95633
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exons 4 and 5 were replaced with a neomycin selection cassette. Gene expression could not be detected by RT-PCR assay. (J:95633)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Ddb2 Mutation:
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9 strains or lines available |
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| References |
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Original: |
J:95633
Yoon T et al.,
"Tumor-prone phenotype of the DDB2-deficient mice."
Oncogene 2005 Jan 13;24(3):469-78
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All: |
5 reference(s)
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Analysis Tools
