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| Nomenclature |
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Symbol:
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Med1tm2Jkr
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Name:
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mediator complex subunit 1;
targeted mutation 2, Janardan K Reddy
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MGI ID: |
MGI:3511276 |
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Synonyms: |
Med1fl, PBPfl |
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Gene:
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Med1
Location:
Chr11:98152154-98193293 bp, - strand
Genetic Position: Chr11,
61.75 cM, cytoband D
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:94123
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Parent Cell Line:
| HM-1 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd-Hprtb-m3
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A single loxP site was introduced in intron 7 and a floxed neomycin cassette was placed in intron 10. The neomycin cassette was later deleted by breeding to EIIa-cre mice leaving exons 8, 9, and 10 flanked by loxP sites. (J:94123)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Med1 Mutation:
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12 strains or lines available |
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| References |
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Original: |
J:94123
Jia Y et al.,
"Transcription coactivator PBP, the peroxisome proliferator-activated receptor (PPAR)-binding protein, is required for PPARalpha-regulated gene expression in liver."
J Biol Chem 2004 Jun 4;279(23):24427-34
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All: |
9 reference(s)
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Analysis Tools
