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| Nomenclature |
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Symbol:
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Traf3ip2tm1.1Lix
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Name:
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TRAF3 interacting protein 2;
targeted mutation 1.1, Xiaoxia Li
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MGI ID: |
MGI:3510784 |
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Synonyms: |
Act1- |
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Gene:
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Traf3ip2
Location:
Chr10:39612934-39655307 bp, + strand
Genetic Position: Chr10,
20.86 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:93923
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Intragenic deletion |
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Mutation details: Act1tm1Lix ES cells were transfected with Cre recombinase to remove the floxed neo and exon 2. RNA blot indicated the absence of transcript in splenic B cells. (J:93923)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Traf3ip2 Mutation:
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20 strains or lines available |
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| References |
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Original: |
J:93923
Qian Y et al.,
"Act1, a negative regulator in CD40- and BAFF-mediated B cell survival."
Immunity 2004 Oct;21(4):575-87
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All: |
10 reference(s)
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Analysis Tools
