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| Nomenclature |
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Symbol:
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Gp1bbtm1Ware
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Name:
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glycoprotein Ib, beta polypeptide;
targeted mutation 1, Jerry Ware
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MGI ID: |
MGI:3510459 |
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Synonyms: |
GP IbbetaNull |
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Gene:
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Gp1bb
Location:
Chr16:18620319-18622403 bp, - strand
Genetic Position: Chr16,
11.53 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:93756
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Parent Cell Line:
| Other (see notes) (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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A targeting vector was designed to replace codons in exon 2 with a neomycin resistance gene. (J:93756)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Gp1bb Mutation:
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4 strains or lines available |
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Notes |
ES cell line = DS2A.
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| References |
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Original: |
J:93756
Kato K et al.,
"Genetic deletion of mouse platelet glycoprotein Ibbeta produces a Bernard-Soulier phenotype with increased alpha-granule size."
Blood 2004 Oct 15;104(8):2339-44
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All: |
1 reference(s)
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Analysis Tools
