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| Nomenclature |
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Symbol:
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Dnmt1tm1(tetO-BCL2)Sjk
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Name:
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DNA methyltransferase (cytosine-5) 1;
targeted mutation 1, Stanley J Korsmeyer
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MGI ID: |
MGI:3497721 |
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Synonyms: |
Dnmt1tm1Sjk, tet-BCL-2 |
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Gene:
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Dnmt1
Location:
Chr9:20907206-20959888 bp, - strand
Genetic Position: Chr9,
7.66 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:93549
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129S4/SvJae
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Mutation
description |
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Allele
Type: | |
Targeted (knock-in) |
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Mutation: | |
Insertion |
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Mutation details: A targeting vector containing human BCL2 under the control of tet operator sequences and a minimal CMV promoter was inserted into the endogenous locus. (J:93549)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Dnmt1 Mutation:
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44 strains or lines available |
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| References |
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Original: |
J:93549
Letai A et al.,
"Antiapoptotic BCL-2 is required for maintenance of a model leukemia."
Cancer Cell 2004 Sep;6(3):241-9
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All: |
1 reference(s)
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Analysis Tools
