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| Nomenclature |
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Symbol:
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Dp(16Cbr1-ORF9)1Rhr
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Name:
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duplication, Chr 16, H R Reeves 1
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MGI ID: |
MGI:3487283 |
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Synonyms: |
Ts1Rhr |
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Gene:
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Dp(16Cbr1-ORF9)1Rhr
Location:
unknown
Genetic Position: Chr16,
Syntenic
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:93223
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Parent Cell Line:
| MC1 (ES Cell) |
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Strain of Origin:
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129S6/SvEvTac
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Mutation
description |
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Allele
Type: | |
Targeted (other) |
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Mutation: | |
Duplication |
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Mutation details: A duplication of a 3.9 Mb region on chromosome 16 was engineered by Cre-mediated recombination between inserted loxP sites located on different chromosomes. This duplicated segment contains mouse orthologs of 33 conserved and minimally conserved genes in the human Down syndrome critical region.
(J:93223)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:93223
Olson LE et al.,
"A chromosome 21 critical region does not cause specific down syndrome phenotypes."
Science 2004 Oct 22;306(5696):687-90
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All: |
11 reference(s)
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Analysis Tools
