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| Nomenclature |
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Symbol:
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MaoaK284stop
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Name:
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monoamine oxidase A;
K284stop
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MGI ID: |
MGI:3057337 |
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Synonyms: |
MaoaA863T, MAO A KO |
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Gene:
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Maoa
Location:
ChrX:16619698-16687818 bp, + strand
Genetic Position: ChrX,
11.78 cM, cytoband A2
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Mutation
origin |
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Strain of Origin:
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129S6/SvEvTac
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Mutation
description |
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Allele
Type: | |
Spontaneous |
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Mutation: | |
Single point mutation |
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A transversion at nucleotide 863 in exon 8 created a stop codon at residue 284 rather than a lysine. (J:93356, J:136818)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:93356
Chen K et al.,
"A spontaneous point mutation produces monoamine oxidase A/B knock-out mice with greatly elevated monoamines and anxiety-like behavior."
J Biol Chem 2004 Oct 17;279(38):39645-52
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All: |
8 reference(s)
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Analysis Tools
