Tg(Myh6-Ppp3ca)37Eno
Transgene Detail
|
|
| Nomenclature |
|
Symbol:
|
Tg(Myh6-Ppp3ca)37Eno
|
|
Name:
|
transgene insertion 37, Eric N Olson
|
|
MGI ID: |
MGI:3056186 |
|
Synonyms: |
CalTG, CN, CNA, MHC-CnA |
|
Transgene:
|
Tg(Myh6-Ppp3ca)37Eno
Location:
unknown
|
|
Transgene origin |
|
Transgene description |
|
Transgene
Type: | |
Transgenic (random, expressed) |
|
Mutation: | |
Insertion |
| |
|
Mutation details: The promoter region of Myh6 drives expression of a constitutively active Ppp3ca cDNA in cardiomyocytes. This is a representative record representing Tg46, Tg22, Tg110, Tg106, Tg108, Tg41, Tg37, and Tg39 which vary in the number of copies of the transgene integrated but all have identical phenotypes. (J:93176)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
| References |
|
Original: |
J:93176
Molkentin JD et al.,
"A calcineurin-dependent transcriptional pathway for cardiac hypertrophy."
Cell 1998 May 17;93(2):215-28
|
|
All: |
33 reference(s)
|
|
|