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| Nomenclature |
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Symbol:
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Brca2tm1Mhun
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Name:
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breast cancer 2;
targeted mutation 1, MC Hung
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MGI ID: |
MGI:3055613 |
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Gene:
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Brca2
Location:
Chr5:150522630-150569746 bp, + strand
Genetic Position: Chr5,
89.52 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:89083
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Parent Cell Line:
| AB1 (ES Cell) |
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Strain of Origin:
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129S7/SvEvBrd-Hprt+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A 2kb 3' region of exon 11 was replaced with a neomycin resistance gene. Targeting was confirmed by Southern blot analysis. (J:89083)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Brca2 Mutation:
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32 strains or lines available |
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| References |
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Original: |
J:89083
Yan DH et al.,
"A delayed chemically induced tumorigenesis in Brca2 mutant mice."
Oncogene 2004 Mar 11;23(10):1896-901
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All: |
1 reference(s)
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Analysis Tools
