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| Nomenclature |
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Symbol:
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Rassf5tm1Kina
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Name:
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Ras association (RalGDS/AF-6) domain family member 5;
targeted mutation 1, Tatsuo Kinashi
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MGI ID: |
MGI:3054868 |
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Synonyms: |
RAPL- |
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Gene:
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Rassf5
Location:
Chr1:131176410-131245258 bp, - strand
Genetic Position: Chr1,
56.91 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:92670
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Parent Cell Line:
| TT2 (ES Cell) |
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Strain of Origin:
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(C57BL/6NCrlj x CBA/JNCrlj)F1
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A neomycin resistance cassette (pLNTK) replaced exon 1 in the gene, including the initiation methionine of the protein. Northern blot analysis of spleen showed no detectable mRNA. Immunoblot analysis of spleen and thymus did not detect protein. (J:92670)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Rassf5 Mutation:
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2 strains or lines available |
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| References |
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Original: |
J:92670
Katagiri K et al.,
"Crucial functions of the Rap1 effector molecule RAPL in lymphocyte and dendritic cell trafficking."
Nat Immunol 2004 Oct;5(10):1045-51
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All: |
5 reference(s)
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Analysis Tools
