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| Nomenclature |
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Symbol:
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Tg(Myh6-cre/Esr1*)1Jmk
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Name:
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transgene insertion 1, Jeffery D Molkentin
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MGI ID: |
MGI:3050453 |
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Synonyms: |
alphaMHC-Cre-Mer-Cre, alpha-MHC-MerCreMer, MCM, mer, mER-CRE-mER, MerCreMer, Tg(Myh6-cre/Esr1)1Jmk |
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Transgene:
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Tg(Myh6-cre/Esr1*)1Jmk
Location:
unknown
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Transgene
origin |
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Transgene
description |
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Transgene
Type: | |
Transgenic (Cre/Flp) |
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Mutation: | |
Insertion |
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Mutation details: This transgene expresses a cre recombinase/ mutant estrogen receptor ligand binding domain fusion protein under the control of a mouse cardiac-specific alpha-myosin heavy chain promoter. Expression was detected in the juvenile and adult heart, but the protein is inactive until induced with tamoxifen. (J:82027)
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Recombinase activity
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:82027
Sohal DS et al.,
"Temporally regulated and tissue-specific gene manipulations in the adult and embryonic heart using a tamoxifen-inducible Cre protein."
Circ Res 2001 Jul 6;89(1):20-5
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All: |
95 reference(s)
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Analysis Tools
