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| Nomenclature |
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Symbol:
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Gpr98tm1Pwh
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Name:
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G protein-coupled receptor 98;
targeted mutation 1, Perrin C White
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MGI ID: |
MGI:3046273 |
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Synonyms: |
Vlgr1del7TM, VLGR/delTM7 |
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Gene:
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Gpr98
Location:
Chr13:81095068-81633154 bp, - strand
Genetic Position: Chr13,
42.18 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:90899
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Parent Cell Line:
| CJ7 (ES Cell) |
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Strain of Origin:
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129S1/Sv-Oca2+ Tyr+ Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A 691 bp segment including intron 81 and part of exon 82 was replaced with an HA tag, a 6xHis affinity purification tag, and a translation stop codon via homologous recombination. Western blot analysis confirmed expression of a single mutant protein. (J:90899)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:90899
McMillan DR et al.,
"Loss of the transmembrane and cytoplasmic domains of the very large G-protein-coupled receptor-1 (VLGR1 or Mass1) causes audiogenic seizures in mice."
Mol Cell Neurosci 2004 Jun;26(2):322-9
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All: |
4 reference(s)
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Analysis Tools
