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| Nomenclature |
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Symbol:
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Slc37a4tm1Jyc
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Name:
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solute carrier family 37 (glucose-6-phosphate transporter), member 4;
targeted mutation 1, Janice Yang Chou
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MGI ID: |
MGI:3046091 |
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Synonyms: |
G6PT-/-, Glc-6-PT |
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Gene:
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Slc37a4
Location:
Chr9:44398176-44402963 bp, + strand
Genetic Position: Chr9,
24.84 cM, cytoband B
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:86005
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Parent Cell Line:
| J1 (ES Cell) |
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Strain of Origin:
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129S4/SvJae
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: The coding region of exon 1 as well as a portion of intron 1 were replaced with a neo cassette inserted by homologous recombination. Protein was undetected in homozygous mutant mice by Western blot analysis of liver and kidney microsomal preparations. (J:86005)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Slc37a4 Mutation:
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3 strains or lines available |
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| References |
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Original: |
J:86005
Chen LY et al.,
"Impaired glucose homeostasis, neutrophil trafficking and function in mice lacking the glucose-6-phosphate transporter."
Hum Mol Genet 2003 Oct 1;12(19):2547-58
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All: |
4 reference(s)
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Analysis Tools
