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| Nomenclature |
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Symbol:
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Lect2tm1Ymg
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Name:
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leukocyte cell-derived chemotaxin 2;
targeted mutation 1, Satoshi Yamagoe
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MGI ID: |
MGI:3045975 |
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Synonyms: |
LECT2- |
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Gene:
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Lect2
Location:
Chr13:56542460-56548538 bp, - strand
Genetic Position: Chr13,
30.08 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:90961
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Parent Cell Line:
| E14.1 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A pGK-neo cassette replaced all exons. Southern blot and PCR confirmed recombination and RT-PCR indicted lack of transcript in mutant livers. (J:90961)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Lect2 Mutation:
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1 strain or line available |
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| References |
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Original: |
J:90961
Saito T et al.,
"Increase in hepatic NKT cells in leukocyte cell-derived chemotaxin 2-deficient mice contributes to severe concanavalin A-induced hepatitis."
J Immunol 2004 Jul 1;173(1):579-85
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All: |
4 reference(s)
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Analysis Tools
