Tg(Pax6-cre,GFP)1Pgr
Transgene Detail
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| Nomenclature |
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Symbol:
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Tg(Pax6-cre,GFP)1Pgr
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Name:
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transgene insertion 1, Peter Gruss
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MGI ID: |
MGI:3045749 |
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Synonyms: |
Le-Cre, Le-Cre-GFP, Lens-Cre, P0-3.9-GFPCre, Pax6Cre, Pax6(LP)-Cre, Tg(Pax6-cre,GFP)1Pgr |
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Transgene:
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Tg(Pax6-cre,GFP)1Pgr
Location:
unknown
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Transgene
origin |
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Transgene
description |
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Transgene
Type: | |
Transgenic (Cre/Flp) |
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Mutation: | |
Insertion |
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Mutation details: This transgene consists of a 6.5 kb genomic fragment upstream of the murine Pax6 gene, an nlsCre, an IRES, EGFP, and a polyadenylation signal. The Pax6 promoter fragment drives expression of Cre and GFP in the surface ectoderm, developing lens, cornea, and pancreas in transgenic mice. (J:65765)
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Recombinase activity
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:65765
Ashery-Padan R et al.,
"Pax6 activity in the lens primordium is required for lens formation and for correct placement of a single retina in the eye"
Genes Dev 2000 Nov 1;14(21):2701-11
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All: |
69 reference(s)
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Analysis Tools
