|
|
| Nomenclature |
|
Symbol:
|
Recql4tm1Glu
|
|
Name:
|
RecQ protein-like 4;
targeted mutation 1, Guangbin Luo
|
|
MGI ID: |
MGI:3045113 |
|
Synonyms: |
Recql4- |
|
Gene:
|
Recql4
Location:
Chr15:76703553-76710559 bp, - strand
Genetic Position: Chr15,
36.28 cM, cytoband D3
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:97101
|
|
Parent Cell Line:
| AB2.2 (ES Cell) |
|
Strain of Origin:
|
129S7/SvEvBrd-Hprtb-m2
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutations: | |
Insertion, Intragenic deletion |
| |
|
Mutation details: The targted mutation replaces a 1075bp genomic fragment encompassing part of exon 9 through exon 13 of the Recql4 gene with a PGKhprt-mini gene cassette. (J:97101)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
Carrying any Recql4 Mutation:
|
3 strains or lines available |
|
| References |
|
Original: |
J:97101
Mann MB et al.,
"Defective sister-chromatid cohesion, aneuploidy and cancer predisposition in a mouse model of type II Rothmund-Thomson syndrome."
Hum Mol Genet 2005 Mar 15;14(6):813-25
|
|
All: |
1 reference(s)
|
|
Analysis Tools
