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| Nomenclature |
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Symbol:
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Fgfr2tm1Dor
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Name:
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fibroblast growth factor receptor 2;
targeted mutation 1, David M Ornitz
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MGI ID: |
MGI:3044679 |
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Synonyms: |
Fgfr2f, Fgfr2fl, Fgfr2flox, Fgfr2Lox, Fgfr2loxP |
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Gene:
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Fgfr2
Location:
Chr7:130162451-133123350 bp, - strand
Genetic Position: Chr7,
73.19 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:90391
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Parent Cell Line:
| RW-4 (ES Cell) |
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Strain of Origin:
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129X1/SvJ
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: Exons 7 through 10 were flanked by a single loxP site in intron 6 and an FRT-flanked neo cassette with a 3' loxP site in intron 10. (J:90391)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:90391
Yu K et al.,
"Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth."
Development 2003 Jul;130(13):3063-74
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All: |
66 reference(s)
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Analysis Tools
