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| Nomenclature |
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Symbol:
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Tg(INS-MT2A,Tyr)1Pne
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Name:
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transgene insertion 1, Paul N Epstein
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MGI ID: |
MGI:3044323 |
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Synonyms: |
HMT-1 |
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Transgene:
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Tg(INS-MT2A,Tyr)1Pne
Location:
unknown
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Transgene
origin |
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: This transgene expresses the full length human metallothionein II gene under the control of the human insulin promoter and first intron. A second transgene that expresses tyrosinase under the control of the tyrosinase promoter was coinjected with the first transgene, and appears to cosegregate.
(J:90564)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:90564
Chen H et al.,
"Overexpression of metallothionein in pancreatic beta-cells reduces streptozotocin-induced DNA damage and diabetes."
Diabetes 2001 Sep;50(9):2040-6
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All: |
4 reference(s)
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Analysis Tools
