|
|
| Nomenclature |
|
Symbol:
|
Tg(Ins1-Cat,Tyr)25Pne
|
|
Name:
|
transgene insertion 25, Paul N Epstein
|
|
MGI ID: |
MGI:3043843 |
|
Synonyms: |
RipCat |
|
Transgene:
|
Tg(Ins1-Cat,Tyr)25Pne
Location:
unknown
|
|
Transgene
origin |
|
Transgene
description |
|
Transgene
Type: | |
Transgenic (random, expressed) |
|
Mutation: | |
Insertion |
| |
|
Mutation details: The symbol represents a double transgene. In one transgene, a rat insulin I promoter drives the expression of a rat catalase cDNA. Northern blot analysis and immunohistochemistry detected expression of this transgene in pancreatic beta cells. A second transgene that expresses tyrosinase under control of the tyrosinase promoter was coinjected with the first transgene, and apparently cosegregated.
(J:59725)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
| References |
|
Original: |
J:59725
Xu B et al.,
"Overexpression of catalase provides partial protection to transgenic mouse beta cells."
Free Radic Biol Med 1999 Oct;27(7-8):830-7
|
|
All: |
3 reference(s)
|
|
Analysis Tools
