|
|
| Nomenclature |
|
Symbol:
|
Nrxn3tm1Sud
|
|
Name:
|
neurexin III;
targeted mutation 1, Thomas C Sudhof
|
|
MGI ID: |
MGI:3042720 |
|
Gene:
|
Nrxn3
Location:
Chr12:88722876-90334935 bp, + strand
Genetic Position: Chr12,
42.94 cM
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:89452
|
|
Parent Cell Line:
| Not Specified (ES Cell) |
|
Strain of Origin:
|
129
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutations: | |
Insertion, Intragenic deletion |
| |
|
Mutation details: A neo cassette replaced the first exon, which contains the complete 5' UTR, start codon, signal peptide and the first LNS domain. Immunoblotting of mutant brain confirmed lack of protein expression. (J:89452)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
| References |
|
Original: |
J:89452
Missler M et al.,
"Alpha-neurexins couple Ca2+ channels to synaptic vesicle exocytosis."
Nature 2003 Jun 26;423(6943):939-48
|
|
All: |
5 reference(s)
|
|
Analysis Tools
