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| Nomenclature |
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Symbol:
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Amhr2tm3(cre)Bhr
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Name:
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anti-Mullerian hormone type 2 receptor;
targeted mutation 3, Richard R Behringer
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MGI ID: |
MGI:3042214 |
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Synonyms: |
Amh-mis-Cre, Amhr2cre, Amhr2cre, Amhr2-cre, Amhr-2/Cre |
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Gene:
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Amhr2
Location:
Chr15:102445367-102454630 bp, + strand
Genetic Position: Chr15,
57.58 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:89999
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (knock-in) |
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Mutation: | |
Insertion |
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Mutation details: A cassette containing IRES-cre and an FRT-flanked neo cassette was inserted into exon 5 of the endogenous gene. Expression of functional cre recombinase was detected in both male and female gonads and in the Mullerian duct. Based on phenotypic similarity to previously described Amhr2 deficient mice, this allele is putatively null. (J:89999, J:118270)
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Recombinase activity
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:89999
Jamin SP et al.,
"Requirement of Bmpr1a for Mullerian duct regression during male sexual development."
Nat Genet 2002 Nov;32(3):408-10
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All: |
71 reference(s)
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Analysis Tools
