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| Nomenclature |
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Symbol:
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Tg(Col1a1-cre)1Kry
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Name:
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transgene insertion 1, Gerard Karsenty
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MGI ID: |
MGI:3041864 |
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Synonyms: |
2.3kb alpha1(I)-cre, alpha1(1) collagen-Cre, alpha1(I)collagen-Cre, alpha1(I)-Cre, Col1-Cre, Col2.3-Cre, Col-Cre |
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Transgene:
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Tg(Col1a1-cre)1Kry
Location:
unknown
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Transgene origin |
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Transgene description |
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Transgene
Type: | |
Transgenic (Cre/Flp) |
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Mutation: | |
Insertion |
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Mutation details: Sequence encoding cre recombinase was adjoined to 2.3 kb of the Col1a1 promoter. The endogenous Col1a1 promoter is active in osteoblasts throughout their differentiation and, accordingly, expression of cre recombinase was detected exclusively in bone. (J:77071)
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Recombinase activity
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:77071
Dacquin R et al.,
"Mouse alpha1(I)-collagen promoter is the best known promoter to drive efficient Cre recombinase expression in osteoblast."
Dev Dyn 2002 Jun;224(2):245-51
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All: |
61 reference(s)
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