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| Nomenclature |
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Symbol:
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Mettm1Sst
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Name:
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met proto-oncogene;
targeted mutation 1, Snorri S Thorgeirsson
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MGI ID: |
MGI:3041135 |
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Synonyms: |
c-metfl, cMetlox, Metflx, Metlox |
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Gene:
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Met
Location:
Chr6:17463800-17573980 bp, + strand
Genetic Position: Chr6,
7.83 cM, cytoband A2
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:89236
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Parent Cell Line:
| HM-1 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd-Hprtb-m3
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: Exon 16 was left flanked by single loxP sites following cre-mediated excision of floxed neo cassette from intron 16. (J:89236)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:89236
Huh CG et al.,
"Hepatocyte growth factor/c-met signaling pathway is required for efficient liver regeneration and repair."
Proc Natl Acad Sci U S A 2004 Apr 30;101(13):4477-82
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All: |
22 reference(s)
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Analysis Tools
