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| Nomenclature |
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Symbol:
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Pnpla6tm1Mvc
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Name:
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patatin-like phospholipase domain containing 6;
targeted mutation 1, Moses V Chao
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MGI ID: |
MGI:3040330 |
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Synonyms: |
Ntefl, NTEfl, Nteflox |
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Gene:
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Pnpla6
Location:
Chr8:3515384-3544266 bp, + strand
Genetic Position: Chr8,
1.92 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:89288
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: Floxed exons 2-5 remained following the excision of a floxed neomycin resistance gene in the 5' UTR by transient Cre expression. Western blot analysis of homozygous mutant brains indicated protein was present at wild-type levels. (J:89288)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Pnpla6 Mutation:
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6 strains or lines available |
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| References |
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Original: |
J:89288
Akassoglou K et al.,
"Brain-specific deletion of neuropathy target esterase/swisscheese results in neurodegeneration."
Proc Natl Acad Sci U S A 2004 Apr 6;101(14):5075-80
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All: |
2 reference(s)
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Analysis Tools
