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| Nomenclature |
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Symbol:
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Mapk7tm1Jdl
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Name:
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mitogen-activated protein kinase 7;
targeted mutation 1, Jiing-Dwan Lee
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MGI ID: |
MGI:3040180 |
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Synonyms: |
BMKflox, erk5loxP |
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Gene:
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Mapk7
Location:
Chr11:61488812-61494406 bp, - strand
Genetic Position: Chr11,
37.96 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:89215
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: Exons 4-7 were flanked by loxP sites via homologous recombination. Transcript was detected in homozygous mutant livers. (J:89215)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Mapk7 Mutation:
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2 strains or lines available |
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| References |
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Original: |
J:89215
Hayashi M et al.,
"Targeted deletion of BMK1/ERK5 in adult mice perturbs vascular integrity and leads to endothelial failure."
J Clin Invest 2004 Apr;113(8):1138-48
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All: |
11 reference(s)
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Analysis Tools
