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| Nomenclature |
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Symbol:
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Efnb1tm1.1Sor
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Name:
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ephrin B1;
targeted mutation 1.1, Philippe Soriano
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MGI ID: |
MGI:3039290 |
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Synonyms: |
ephrin-B1null |
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Gene:
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Efnb1
Location:
ChrX:99136130-99148991 bp, + strand
Genetic Position: ChrX,
43.22 cM, cytoband D
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:89008
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Parent Cell Line:
| AK7 (ES Cell) |
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Strain of Origin:
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129S4/SvJaeSor
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Cre-mediated recombination removes the floxed exons 2-5 in Ephb1tm1Sor, leaving a PGK-neo-bpA cassette flanked by FRT sites. Western blot of embryo lysates confirmed absence of the endogenous protein. (J:89008, J:143845)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Efnb1 Mutation:
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4 strains or lines available |
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| References |
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Original: |
J:89008
Davy A et al.,
"Ephrin-B1 forward and reverse signaling are required during mouse development."
Genes Dev 2004 Mar 1;18(5):572-83
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All: |
8 reference(s)
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Analysis Tools
