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| Nomenclature |
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Symbol:
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Selltm1Flv
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Name:
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selectin, lymphocyte;
targeted mutation 1, Richard A Flavell
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MGI ID: |
MGI:3039283 |
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Synonyms: |
CD62L- |
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Gene:
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Sell
Location:
Chr1:164062076-164080785 bp, + strand
Genetic Position: Chr1,
71.37 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:89253
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Parent Cell Line:
| D3 (ES Cell) |
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Strain of Origin:
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129S2/SvPas
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A neo cassette replaced 5.5 kb encoding the Sell domain via homologous recombination. Flow cytometry confirmed the absence of protein expression in peripheral blood leukocytes. (J:89253)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Sell Mutation:
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15 strains or lines available |
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| References |
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Original: |
J:89253
Xu J et al.,
"Impaired primary T cell responses in L-selectin-deficient mice."
J Exp Med 1996 Feb 1;183(2):589-98
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All: |
7 reference(s)
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Analysis Tools
