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| Nomenclature |
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Symbol:
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Tg(BCR/ABL1)5Hhi
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Name:
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transgene insertion 5, Hisamaru Hirai
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MGI ID: |
MGI:3039034 |
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Transgene:
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Tg(BCR/ABL1)5Hhi
Location:
unknown
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Transgene origin |
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Strain of Origin:
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(C57BL/6 x DBA/2)F2
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Transgene description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: Fusion gene of human BCR and ABL1 encoding an oncogenic 210 kDa protein (p210BCR/ABL). Expression of the cDNA is controlled by the mouse Tec promoter. (J:46392)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:46392
Honda H et al.,
"Development of acute lymphoblastic leukemia and myeloproliferative disorder in transgenic mice expressing p210bcr/abl: a novel transgenic model for human Ph1-positive leukemias."
Blood 1998 Mar 15;91(6):2067-75
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All: |
7 reference(s)
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