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| Nomenclature |
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Symbol:
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F2rtm1Pago
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Name:
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coagulation factor II (thrombin) receptor;
targeted mutation 1, Patricia Andrade-Gordon
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MGI ID: |
MGI:3038377 |
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Synonyms: |
Par1-, PAR-1-, ThrR- |
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Gene:
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F2r
Location:
Chr13:95601789-95618433 bp, - strand
Genetic Position: Chr13,
50.21 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:38032
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Parent Cell Line:
| E14 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: 0.4 kb of genomic sequence encompassing the proximal promoter region and a 5' portion of exon 1 that included the start codon was replaced with a neo cassette inserted by homologous recombination. Normal transcript was undetected in homozygous mutant mice by Northern blot analysis of kidney tissue. (J:38032)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any F2r Mutation:
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6 strains or lines available |
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| References |
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Original: |
J:38032
Darrow AL et al.,
"Biological consequences of thrombin receptor deficiency in mice."
Thromb Haemost 1996 Dec;76(6):860-6
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All: |
17 reference(s)
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Analysis Tools
