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| Nomenclature |
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Symbol:
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Tg(Tbx1-cre)1Joe
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Name:
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transgene insertion 1, Jonathan A Epstein
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MGI ID: |
MGI:3037834 |
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Synonyms: |
Tbx1-Cre, Tbx1-enCre |
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Transgene:
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Tg(Tbx1-cre)1Joe
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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Not Specified
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Transgene
description |
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Transgene
Type: | |
Transgenic (Cre/Flp) |
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Mutation: | |
Insertion |
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Mutation details: Sequence encoding cre recombinase was adjoined to mouse Tbx1 promoter sequence that extended 16 kb from the start codon and included the proximal promoter and three conserved enhancer regions. The expression pattern of cre recombinase recapitulated that of Tbx1, with expression observed in the mesenchyme, otic vesicle, and somites during development. (J:88814)
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Recombinase activity
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:88814
Brown CB et al.,
"Cre-mediated excision of Fgf8 in the Tbx1 expression domain reveals a critical role for Fgf8 in cardiovascular development in the mouse."
Dev Biol 2004 Mar 1;267(1):190-202
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All: |
3 reference(s)
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Analysis Tools
