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| Nomenclature |
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Symbol:
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Elk4tm1Rtr
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Name:
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ELK4, member of ETS oncogene family;
targeted mutation 1, Richard Treisman
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MGI ID: |
MGI:3036598 |
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Synonyms: |
SAP-1- |
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Gene:
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Elk4
Location:
Chr1:132007607-132032612 bp, + strand
Genetic Position: Chr1,
57.24 cM, cytoband E3-G
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:88515
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A portion of exon 1 and all of exons 2 and 3 were replaced with an IRES-lacZ-neo cassette. Transcript was undetected in the thymi of homozygous mutant mice by RNAse protection. lacZ expression was not reported. (J:88515)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Elk4 Mutation:
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8 strains or lines available |
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| References |
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Original: |
J:88515
Costello PS et al.,
"Ternary complex factor SAP-1 is required for Erk-mediated thymocyte positive selection."
Nat Immunol 2004 Mar;5(3):289-98
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All: |
3 reference(s)
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Analysis Tools
