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| Nomenclature |
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Symbol:
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Vsx1tm1Mci
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Name:
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visual system homeobox 1 homolog (zebrafish);
targeted mutation 1, Roderick R McInnes
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MGI ID: |
MGI:3033929 |
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Synonyms: |
Vsx1 delta 1-4 |
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Gene:
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Vsx1
Location:
Chr2:150680699-150689360 bp, - strand
Genetic Position: Chr2,
74.74 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:88182
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A genomic fragment, encompassing a portion of exon 1 and all of exons 2 through 4, was replaced with a neomycin selection cassette inserted by homologous recombination. 86 bp of the exon 1 coding region, as well as the coding region of exon 5, were left intact, however no protein was detected in homozygous mutant retinal tissue by immunofluorescence. (J:88182)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Vsx1 Mutation:
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0 strains or lines available |
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| References |
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Original: |
J:88182
Chow RL et al.,
"Control of late off-center cone bipolar cell differentiation and visual signaling by the homeobox gene Vsx1."
Proc Natl Acad Sci U S A 2004 Feb 10;101(6):1754-9
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All: |
4 reference(s)
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Analysis Tools
