|
|
| Nomenclature |
|
Symbol:
|
Tg(Ipf1-cre)6Tuv
|
|
Name:
|
transgene insertion 6, David A Tuveson
|
|
MGI ID: |
MGI:3032531 |
|
Synonyms: |
Pdx1-cre, PDX-1-Cre, Tg(Ipf1-cre)1Tuv |
|
Transgene:
|
Tg(Ipf1-cre)6Tuv
Location:
unknown
|
|
Ctnnb1tm4Wbm/Ctnnb1tm4Wbm Tg(Ipf1-cre)6Tuv/? pancreata display extensive loss of exocrine tissue
Show the 2 image(s) involving this allele.
|
 |
|
Transgene
origin |
|
Transgene
description |
|
Transgene
Type: | |
Transgenic (Cre/Flp) |
|
Mutation: | |
Insertion |
| |
|
Mutation details: The transgenic construct is composed of a Cre recombinase coding sequence under the control of the Ipf1 promoter. Cre expression is thus directed to islet cells of the pancreas. (J:87973)
|
|
|
Recombinase activity
|
|
Driver:
|
Pdx1
Summary of all recombinase alleles
driven by Pdx1.
|
|
MGI has not yet included tissue activity data for this allele in any anatomical systems.
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
| References |
|
Original: |
J:87973
Hingorani SR et al.,
"Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse."
Cancer Cell 2003 Dec;4(6):437-50
|
|
All: |
48 reference(s)
|
|
Analysis Tools
