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| Nomenclature |
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Symbol:
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mdac
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Name:
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modifier of Dac;
recessive modifier of Dac
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MGI ID: |
MGI:3027244 |
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Gene:
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Mdac
Location:
unknown
Genetic Position: Chr13,
Syntenic
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Mutation origin |
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Strain of Origin:
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multiple strains
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Mutation description |
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Allele
Type: |
Spontaneous |
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Inheritance: |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Mdac Mutation:
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0 strains or lines available |
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Notes |
Presence of this allele in the homozygous state is necessary for expression of dactylaplasia in Dac/+ mice. It is homozygous in strains SM, BALB/c, LG, and 129/J. The dominant allele occurs in strains C57BL/6, DBA/2, CBA/J, AKR, and SWR. There is no visible effect on the feet of mdac/mdac in the absence of Dac alleles (J:6607).
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| References |
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Original: |
J:6607
Chai CK,
"Dactylaplasia in mice a two-locus model for development anomalies."
J Hered 1981 Jul-Aug;72(4):234-7
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All: |
5 reference(s)
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