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| Nomenclature |
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Symbol:
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Urodtm1Kush
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Name:
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uroporphyrinogen decarboxylase;
targeted mutation 1, James P Kushner
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MGI ID: |
MGI:2687172 |
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Synonyms: |
URO-D- |
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Gene:
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Urod
Location:
Chr4:116989965-116994413 bp, - strand
Genetic Position: Chr4,
53.41 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:66704
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Disruption caused by insertion of vector |
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Mutation details: A fragment encompassing exon 6 and portions of its flanking introns was replaced with a neomycin selection cassette inserted by homologous recombination. (J:66704)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Urod Mutation:
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2 strains or lines available |
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| References |
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Original: |
J:66704
Phillips JD et al.,
"A mouse model of familial porphyria cutanea tarda."
Proc Natl Acad Sci U S A 2001 Jan 2;98(1):259-64
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All: |
2 reference(s)
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Analysis Tools
