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| Nomenclature |
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Symbol:
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Cdkn2atm1(GFP)Cjs
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Name:
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cyclin-dependent kinase inhibitor 2A;
targeted mutation 1, Charles J Sherr
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MGI ID: |
MGI:2684603 |
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Synonyms: |
Arf-, ArfGFP, Cdkn2atm2Cjs |
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Gene:
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Cdkn2a
Location:
Chr4:89274473-89294653 bp, - strand
Genetic Position: Chr4,
42.15 cM, cytoband C3-C6
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:87339
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Parent Cell Line:
| W9.5/W95 (ES Cell) |
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Strain of Origin:
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129S1/Sv-Oca2+ Tyr+ Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exon 1B of the Arf gene was replaced with a GFP cassette, thereby disabling the Arf function and placing GFP under the control of the Arf promoter. (J:87339)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:87339
Zindy F et al.,
"Arf tumor suppressor promoter monitors latent oncogenic signals in vivo."
Proc Natl Acad Sci U S A 2003 Dec 23;100(26):15930-5
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All: |
15 reference(s)
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Analysis Tools
