|
|
| Nomenclature |
|
Symbol:
|
Twist1Pas
|
|
Name:
|
twist basic helix-loop-helix transcription factor 1;
Pasteur
|
|
MGI ID: |
MGI:2684436 |
|
Synonyms: |
Pdt |
|
Gene:
|
Twist1
Location:
Chr12:33957671-33959817 bp, + strand
Genetic Position: Chr12,
14.81 cM, cytoband B-C1
|
|
Polydactyly in the right hindlimb of Twist1Pas/Twist1+ mice
Show the 1 image(s) involving this allele.
|
 |
|
Mutation
origin |
|
Mutation
description |
|
Allele
Type: | |
Chemically induced (ENU) |
|
Mutation: | |
Undefined |
| |
|
Mutation details: This ENU induced mutation was found to be alleleic through complementation analysis with a known allele at the Twist1 locus. No sequence alteration was found in the coding region of the gene. A decrease in transcript was noted by in situ hybridization. (J:86815)
|
|
Inheritance: | |
Semidominant |
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
| References |
|
Original: |
J:8293
Shedlovsky A et al.,
"Induction of recessive lethal mutations in the T/t-H-2 region of the mouse genome by a point mutagen."
Genet Res 1986 Apr;47(2):135-42
|
|
All: |
2 reference(s)
|
|
Analysis Tools
