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| Nomenclature |
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Symbol:
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Cdc25btm1Pjd
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Name:
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cell division cycle 25B;
targeted mutation 1, Peter J Donovan
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MGI ID: |
MGI:2682953 |
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Synonyms: |
Cdc25b- |
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Gene:
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Cdc25b
Location:
Chr2:131186949-131198497 bp, + strand
Genetic Position: Chr2,
63.29 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:87011
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A 4.0 kb region encoding the phosphatase box was replaced with a neomycin selection cassette inserted by homologous recombination. Protein was undetected by Western blot analysis of homozygous mutant MEF extracts using an N-terminal antibody. (J:87011)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Cdc25b Mutation:
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3 strains or lines available |
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| References |
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Original: |
J:87011
Lincoln AJ et al.,
"Cdc25b phosphatase is required for resumption of meiosis during oocyte maturation."
Nat Genet 2002 Apr;30(4):446-9
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All: |
5 reference(s)
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Analysis Tools
